Today i have installed Softbiz Ad Management PLUS on site.
The script written in PHP with MySQL database. Setting up is really easy, create a MySQL database, import data from db/SoftbizAdManagementPLUSScript.sql file, then edit two configuration files and put MySQL database details.
This script allow your visitors to signup and buy banner or text advertisement on your web site or network. It allow Impression based or PPC (Pay Per Click – like Google AdSense, but no content targeting).
If you just need banner management, no customer signup and payment solution, phpAdsNew will work great. I am currently using phpAdsNew.